Which hypothalamic hormone stimulates the synthesis and release of FSH and LH?

Gonadotropin Releasing Hormone (GnRH) is the hypothalamic hormone responsible for stimulating the synthesis and release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary gland. GnRH is secreted in a pulsatile manner, which is crucial for the proper function of the reproductive system. When GnRH is released into the portal circulation, it binds to specific receptors on the pituitary gonadotropes, leading to the production and subsequent secretion of FSH and LH.

FSH plays a significant role in regulating the development and function of reproductive processes, such as the maturation of ovarian follicles in females and spermatogenesis in males. LH is critical for triggering ovulation and stimulating testosterone production in males. The action of GnRH is thus essential for normal reproductive health and functioning.

Other hormones listed do not have this stimulating effect on FSH and LH. Growth Hormone Releasing Hormone (GHRH) mainly stimulates the release of growth hormone, while Prolactin Inhibiting Factor (Dopamine) inhibits prolactin release. Corticotropic Releasing Hormone (CRH) is involved in the stress response, stimulating the release