Which enzyme is produced in the lungs as part of the Renin-angiotensin-aldosterone system?

The enzyme produced in the lungs as part of the Renin-angiotensin-aldosterone system is Angiotensin Converting Enzyme (ACE). ACE is crucial for the conversion of angiotensin I, which is an inactive precursor, into angiotensin II, a potent vasoconstrictor that plays a significant role in increasing blood pressure and stimulating the release of aldosterone from the adrenal glands.

This system is vital for regulating blood pressure and fluid balance in the body. While angiotensinogen is produced by the liver and renin is released by the kidneys, it is ACE in the lungs that facilitates the conversion necessary for the system to exert its effects. Aldosterone itself is a hormone that gets released as a result of this cascade but is not produced in the lungs; rather, it acts on the kidneys to promote sodium and water retention. Understanding the role of ACE helps clarify the process and the importance of lung function in regulating cardiovascular dynamics.