Which enzyme converts angiotensin I to angiotensin II?

The enzyme that converts angiotensin I to angiotensin II is angiotensin-converting enzyme (ACE). This conversion is a crucial step in the renin-angiotensin-aldosterone system (RAAS), which plays a significant role in regulating blood pressure and fluid balance within the body. Angiotensin I, which is formed from angiotensinogen through the action of renin, is relatively inactive. ACE catalyzes the conversion process, transforming angiotensin I into the more active form, angiotensin II. Angiotensin II is a potent vasoconstrictor and significantly impacts cardiovascular function and homeostasis by promoting increased blood pressure and stimulating aldosterone secretion from the adrenal glands, which facilitates sodium and water retention.

While renin is involved in producing angiotensin I from angiotensinogen, it does not perform the conversion to angiotensin II. Angiotensinase and kinase do not play a direct role in the context of this specific conversion process.