What is a key role of Cortisol in the body?

Prepare for the NBEO General Physiology Exam. Study with detailed flashcards and multiple choice questions, each with explanations. Ensure success on your exam!

Cortisol plays a significant role in suppressing the immune response, which is critical for managing stress and inflammation in the body. Produced by the adrenal glands, cortisol is often referred to as the "stress hormone" because its levels increase during stressful situations. One of its functions is to prevent overactivity of the immune system, helping to reduce inflammation and limit the body's immune response to prevent it from becoming excessive, which can lead to tissue damage.

Thus, during times of stress or injury, cortisol helps to balance the immune response, ensuring that the body can manage stress effectively without triggering an inflammatory response that could cause further harm. While cortisol may have effects on other systems, such as regulating glucose metabolism and influencing the metabolism of fats and proteins, its key role in modulating the immune system is central to maintaining homeostasis during periods of stress.

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