What is a key characteristic of the Distal Convoluted Tubule when it comes to water?

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The Distal Convoluted Tubule (DCT) is known for being relatively impermeable to water under normal physiological conditions. This characteristic is crucial for the regulation of water and electrolyte balance in the body. Unlike the proximal convoluted tubule and the loop of Henle, where water reabsorption can occur more freely, the DCT's low permeability means that water reabsorption in this segment is minimal unless influenced by specific hormones, such as aldosterone or antidiuretic hormone (ADH). These hormones act to increase water reabsorption when necessary, but in their absence, the DCT maintains its impermeable nature, thus playing an important role in urine concentration and overall homeostasis.

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