Does Somatostatin inhibit or stimulate insulin secretions?

Somatostatin is a peptide hormone that plays a crucial role in the regulation of various endocrine functions, particularly in the pancreas. It is produced by the delta cells of the islets of Langerhans and has the primary function of inhibiting the secretion of several hormones, including insulin and glucagon.

When somatostatin is released, it works to decrease the secretion of insulin from the beta cells of the pancreas. This inhibition is important for maintaining glucose homeostasis, as excessive insulin release can lead to hypoglycemia (low blood sugar). By inhibiting insulin secretion, somatostatin ensures that the levels of insulin in the bloodstream remain balanced, allowing for proper metabolic control.

In summary, somatostatin acts as a regulatory hormone that inhibits insulin secretion, thereby contributing to the fine-tuning of energy metabolism within the body.